Their patioent info states: "Who should not take Zelnorm? You should not start taking Zelnorm if: You now have diarrhea or have diarrhea often. You have bad kidney or liver disease. You have ever had bowel obstruction (intestinal blockage), symptomatic gallbladder disease, or abdominal adhesions causing pain and/or intestinal blockage. You are allergic to Zelnorm or any of its ingredients. The active ingredient in Zelnorm is tegaserod maleate. The inactive ingredients are listed at the end of this page. "