Re: Crazy enzyme treatment suggestion?!

From: Huong Nguyen, PharmD (
Tue Jul 23 10:21:26 2002

At Thu, 8 Feb 2001, MLWhitworth, MD wrote: >
>I use serracea (extract of the Pitcher plant) in the form of Serapin
>(High Chemical Co) and hyaluronidase (Wydase) for scar tissue. The
>Serapin is injectable peripherally but some use it in the epidural
>space...I am unsure of the degree if its use here...
>The Wydase is used as part of epiduroscopy or the Racz procedure to help
>with lysis of adhesions in the epidural space. It is an injectable
>agent in the epidural space. In the past there were studies reporting
>its use in arachnoiditis, but later it was found some of those patients
>became worse after an intrathecal injection of Wydase...
>MLWhitworth, MD
>At Thu, 8 Feb 2001, Zoe wrote:
>>Thanks Jenny,
>>I'll asked today and get back to you.
>>At Thu, 8 Feb 2001, jenny low wrote:
>>>Hi Zoe,
>>>I've never heard of either of those enzymes. How are they administered? Are
>>>they oral or by injections? Ask if they are available in the states?
>>>Do you have to have a prescription or is it something you could get at a
>>>health food store? I don't know. Just thought I would throw in some
>>>questions that you could ask. I hope you find out something good!
>>>>From: (Zoe)
>>>>To: Multiple recipients of list ADHESIONS
>>>>Subject: Crazy enzyme treatment suggestion?!
>>>>Date: Wed, 7 Feb 2001 11:35:38 -0600
>>>>Hi all,
>>>>I was talking to a Pharmacologist today and he said that the enzyme
>>>>"Serratia Paptidase" is very effective for breaking down surgical
>>>>adhesions! He also named the enzyme " Hyaluronidase" as a treatment too.
>>>>Have any of you heard about this at all? He seemed to think that it was
>>>>definately a way to go rather than surgery.
>>>>Please comment.
>>>>He's only around for a week so I need to pick his brains as much as
>>>>possible about it. So please send me any questions you might have.
>>>>Zoe (UK)

>>Zoe (UK)


I have further questions about the use of wydase. do you know of any current literature supporting the use of hyaluronidase as IT or an epidural? And of so, would the compounding formula (with base: thiomerosal) be compitable for such administration? If not, would you simply just need to make it in NaCl? Thank you deeply for your help!

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