Re: Fibrin Glue...a special kind of glue being used in surgical procedures.

From: Anne Hayashi (mhaya0902@aol.com)
Thu Jul 6 12:47:35 2000


At Thu, 6 Jul 2000, Helen Dynda wrote: >
>Fibrin Glue and Fibrin sealant are not known as " super glue." How would Fibrin Glue ( also known as Fibrin Sealant ) be effective on adhesions? This product prevents bleeding from occuring. There are very few surgical procedures in which this product is used. The 12 articles ( below ) will give you some idea as to what procedures Fibrin Glue is used for. Dr. Bradley's use of fibrin sealant is the only evidence, which I have been able to find, that fibrin sealant has been used to prevent adhesions in the abdominal/pelvic cavity.
> I have asked Dr. Wiseman about the possibility of using

Intergel (as the glue) in conjunction with Interceed. He didn't think this would work, that the Interceed would be washed out, I believe. So, even with complete homeostasis, we are still left with the problem of raw sticky surfaces on the peritoneal wall, and raw sticky surfaces underneath. I wouldn't think this was a problem if there is enough space between surfaces, and the use of 300 ml of ringers might work for flotation. However, around the rectum, sigmoid, bladder, everything is packed in there pretty tight, and unfortunately for me it didn't work. However, I did not have surgery with Drs. Reich, and Redan, and perhaps they are able to lick that problem. I have my tapes, so if there is any interest in viewing the surgeries, I would be happy to send them. These tapes have audio (the surgeon's description), so they might be a little more interesting, however, I think, on the other hand they might be a great cure for insomnia.

>Dr. Harry Reich and Dr. Jay Redan - from the NEW Adhesions Unit in Scranton, PA - believe that ADHESIONS FORM AS A RESULT OF ANY BLOOD or other debris that is left in the abdominal/pelvic cavity. Therefore, these adhesion specialists try to be as meticulous as possible * throughout the entire surgical procedure * - by continually moistening the tissues and at the same time removing every trace of blood or other debris.
>
>Marla said, "Adhesions are neither a wound nor do they bleed." BUT blood/bleeding is believed to be the cause of the adhesions in the first place. When the blood or bleeding is taken care of properly, chances are that NO adhesions will form...or...adhesion formation will be greatly minimized. Since I am not a medical professional, I have tried to answer your question to the best of my ability.
>
>~ ~ ~ ~
>
>At Thu, 6 Jul 2000, Marla wrote:
>
>Yes, I understand it's use for closing wounds and stopping bleeding. But
>adhesions are neither a wound nor do they bleed. How would super glue be
>effective on adhesions?
>
>Thanks
>Marla
>
>http://www.soltec.net/~onery1
>
>~ ~ ~ ~
>
>From: Marla (onery1@soltec.net) -- Wed, 5 Jul 2000
>
>Question - How does any of this apply to using glue in the peritoneal cavity. I mean think what would happen if it got on your intestines. Ewww.
>
>~ ~ ~ ~
>
>From: Helen Dynda (olddad66@runestone.net) -- Thu, 6, Jul 2000
>
>ANSWER: I actually remember Dr. J. Glenn Bradley saying that he has used
>fibrin glue in the peritoneal cavity - to stop the bleeding.
>
>Someone suggested, "Why don't they use glue?" Here is evidence that glue is
>already being used...a special kind of glue - fibrin glue - for special
>kinds of surgical procedures!!
>
>~ ~ ~ ~
>
>From: Helen Dynda (olddad66@runestone.net) -- Wed, 5 Jul 2000
>
>1.) Effect of Hemostat Agent (Fibrin Glue) for Hemostasis in Cementless
>Total Knee Arthroplasty
>http://www.aaos.org/wordhtml/anmeet94/sciprog/419.htm
>
>2.) New Fibrin Sealant Approved to Help Control Bleeding in Surgery
>
>http://www.fda.gov/bbs/topics/ANSWERS/ANS00865.html.)
>
>3.) Neither Sutures Nor Staples Have Inherent Sealing Characteristics
>
>http://www.fusionmed.com/market/cneeds.html#topFloSeal Matrix
>
>4.) FloSeal Matrix http://www.fusionmed.com/product/floseal.html
>
>5.) Fibrin sealant reduces fluid accumulation after breast surgery
>http://www.imaginiscorp.com/breasthealth/news/news10.21.99.html
>
>6.) Re: Fibrin Glue for Anal Fistula -- Posted by HFHSM.D. on June 17, 1998
>
>http://www.medhelp.org/perl6/gastro/archive/1054.html
>
>7.) Fibrin glues
>
>http://www.medicine.ox.ac.uk/ohc/fibglue.htm
>
>8.) Fibrin Glue Stops Ulcerous Bleeding -- In order to read this article, you will have to enter the Url onto the address-line of your computer monitor ( or screen ).
>
>http://news.medscape.com/jobson/MedTrib/interncard/1997/v38.n17/FibrinGl eStopsUlcerousBle.html
>
>9.) Fibrin Glue Reduces Risks From Circumcision in Patients With Hemophilia
>http://www.mmhc.com/hemo/articles/hemov6n3/avnoglu.html
>
>10.) Tisseel® VH Fibrin Sealant
>
>http://www.nhsusa.com/tisseel.html
>
>11.) Fibrin Sealant Demonstrates Reduced Complications From Breast Cancer
>Surgery
>
>http://www.pslgroup.com/dg/3df72.htm
>
>12.) Injection Of Fibrin Glue To Treat Bleeding Ulcers
>
>http://www.pslgroup.com/dg/36b56.htm


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