Hi, I was not aware that you can go without your Large intestines. WOW I had my surgery at a Teaching Hospital and they use that Sephrin too and I hope it works its been 3 months i have pain to the touch which is ok i guess but i can go to the bathroom with no problem. I drink PLUM START it new drink on the market its wonderful. And i eat Prunes another new thing on the market call THE ONE. I hope i don't need anymore surgery i am so fed up. I have a frozen shoulder i am dealing with right now. AS anyone suffered from that. VAL