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Dose conversion between opiates Article 5 Med Change from (total daily dose in mg) Change to (total daily dose in mg)
Oral codeine Oral dihydro- codeine Oral pethidine Oral morphine Oral dextro- moramide Morphine infusion Diamorphine infusion Oral hydro- morphone Sublingual buprenorphine
Divide by 12.5 Divide by 10
Multiply by 2 Multiply by 3 Multiply by 4 Multiply by 7.5 Multiply by 50 Oral morphine
Divide by 25 Divide by 20 Divide by 2
Multiply by 1.5 Multiply by 4 Multiply by 25 Oral dextromoramide
Divide by 40 Divide by 30 Divide by 3 Divide by 1.5
Multiply by 1 Multiply by 2.5 Multiply by 20 Morphine infusion
Divide by 40 Divide by 30 Divide by 3 Divide by 1.5 Divide by 1
Multiply by 2.5 Multiply by 20 Diamorphine infusion
Divide by 100 Divide by 75 Divide by 7.5 Divide by 4 Divide by 2.5
Multiply by 7 Oral hydromorphone
Divide by 50 Divide by 25 Divide by 20 Divide by 7
Intended as a guide only - titrate individually according to pain, response and side effects.